5 minutes for
Dreaming

Gain 5 minutes of time every day by switching from tablet solution to powder. Find out what you can do with the time saved!

What can you do in five minutes?

SPORT

Challenge accepted! Let's tackle this plank exercise head-on. Aim to maintain the plank position for a solid 40 seconds, then give yourself a well-deserved 20-second break. Repeat this cycle five times, and remember to stay motivated throughout the process.

Go for a brief stroll. Just dedicating five minutes to walking, in addition to engaging in other activities, can have a noticeable impact on your overall fitness level.

In search of a quick and effective workout? Try performing 30 seconds of squats, followed by 30 seconds of push-ups, for a total of 5 repetitions. Feel the surge of energy coursing through your body as you engage in this dynamic routine.

Challenge accepted! Let's tackle this plank exercise head-on. Aim to maintain the plank position for a solid 40 seconds, then give yourself a well-deserved 20-second break. Repeat this cycle five times, and remember to stay motivated throughout the process.

Go for a brief stroll. Just dedicating five minutes to walking, in addition to engaging in other activities, can have a noticeable impact on your overall fitness level.

In search of a quick and effective workout? Try performing 30 seconds of squats, followed by 30 seconds of push-ups, for a total of 5 repetitions. Feel the surge of energy coursing through your body as you engage in this dynamic routine.

WELLBEING

What could be more exhilarating than amplifying your favorite song to its maximum volume and surrendering yourself to the joy of dancing?

Indulging in the affectionate company of your fluffy pet and sharing moments of warmth and cuddles can be immensely rewarding—for both you and your beloved companion.

Grabbing a piece of paper and allowing your thoughts to flow freely onto its surface can be a powerful and transformative experience.

What could be more exhilarating than amplifying your favorite song to its maximum volume and surrendering yourself to the joy of dancing?

Indulging in the affectionate company of your fluffy pet and sharing moments of warmth and cuddles can be immensely rewarding—for both you and your beloved companion.

Grabbing a piece of paper and allowing your thoughts to flow freely onto its surface can be a powerful and transformative experience.

ACTIVITIES FOR CHILDREN

Embark on an unforgettable adventure alongside your favorite heroes as you eagerly flip through the pages of an exhilarating comic book.

Construct an extraordinary fortress of pillows using chairs, sofas, blankets, and an array of soft cushions, creating the perfect setting for an unforgettable and epic pillow fight!

Reach out to your grandparents and share the story of how you managed to save five precious minutes of your day.

Embark on an unforgettable adventure alongside your favorite heroes as you eagerly flip through the pages of an exhilarating comic book.

Construct an extraordinary fortress of pillows using chairs, sofas, blankets, and an array of soft cushions, creating the perfect setting for an unforgettable and epic pillow fight!

Reach out to your grandparents and share the story of how you managed to save five precious minutes of your day.

MUSIC

Curate a personalized playlist filled with the latest and greatest songs, and then spread the joy by sharing it with your friends.

Begin your day on a delightful note by tuning in to your favorite radio station during breakfast, setting a positive and uplifting mood to kickstart your morning.

Embrace the musical journey by grabbing your instrument and exploring the realms of new melodies and harmonies.

Curate a personalized playlist filled with the latest and greatest songs, and then spread the joy by sharing it with your friends.

Begin your day on a delightful note by tuning in to your favorite radio station during breakfast, setting a positive and uplifting mood to kickstart your morning.

Embrace the musical journey by grabbing your instrument and exploring the realms of new melodies and harmonies.

ORIGAMI

Engage in a playful origami challenge by folding your own delightful frog and inviting your friends to join in the fun. Who can achieve the longest jump?

Transform your window into a vibrant aquarium by crafting adorable paper fish, adding a touch of charm and whimsy to your living space.

Embrace the charm of turtles, those delightful creatures, by crafting your very own paper versions and setting them on whimsical adventures before bidding them farewell.

Engage in a playful origami challenge by folding your own delightful frog and inviting your friends to join in the fun. Who can achieve the longest jump?

Transform your window into a vibrant aquarium by crafting adorable paper fish, adding a touch of charm and whimsy to your living space.

Embrace the charm of turtles, those delightful creatures, by crafting your very own paper versions and setting them on whimsical adventures before bidding them farewell.

CREATIVE RECYCLING

Are you tired of never finding the perfect pen when you need it? Consider constructing a custom pen holder for your desk.

Create a mesmerizing rain stick to evoke the soothing sounds of rainfall, bringing a sense of tranquility and harmony to your space.

Welcome the essence of spring into your home by crafting exquisite cardboard butterflies, adding a touch of natural beauty to your surroundings

Are you tired of never finding the perfect pen when you need it? Consider constructing a custom pen holder for your desk.

Create a mesmerizing rain stick to evoke the soothing sounds of rainfall, bringing a sense of tranquility and harmony to your space.

Welcome the essence of spring into your home by crafting exquisite cardboard butterflies, adding a touch of natural beauty to your surroundings

What is Phenylketonuria?

Phenylketonuria (PKU) is a rare hereditary metabolic disease. The body, which normally absorbs the amino acid phenylalanine (Phe) from many foods, is unable to completely convert it into the amino acid tyrosine (Tyr) in the presence of this disease. The culprit for this anomaly is a defective ‘motor’ enzyme: phenylalanine hydroxylase (PAH). This defect therefore prevents the interaction between the motor and the fuel tetrahydrobiopterin (BH4) and the subsequent conversion of Phe into Tyr. In 1978, Dr. Schircks was the first chemist to develop the active ingredient sapropterin dihydrochloride, thus offering sufferers an enormous opportunity for treatment.

How PKU can be treated

As high blood Phe concentrations are strongly related to neurocognitive outcome, existing treatments aim at decreasing blood Phe concentrations. Treatments include strictly controlled phenylalanine (Phe) amount intakes through diet in combination with Phe-free L-amino acid supplements, and also pharmacological treatments, such as sapropterin dihydrochloride, which helps restoring Phe metabolism.

Diets for PKU patients require severely restricting or even eliminating foods of high phenylalanine content, such as meat, fish, nuts, cheese, legumes, and other dairy products.
Starchy foods such as potatoes, bread, pasta, and corn must be monitored. Infants may still be breastfed to provide all of the benefits of breast milk, but the quantity may need to be limited, resulting in necessary supplementation of missing nutrients. Many diet foods and diet soft drinks containing aspartame sweetener must also be avoided. Today most physicians recommend that PKU patients must keep monitoring their Phe levels throughout their entire life.

How PKU can be treated

As high blood Phe concentrations are strongly related to neurocognitive outcome, existing treatments aim at decreasing blood Phe concentrations. Treatments include strictly controlled phenylalanine (Phe) amount intakes through diet in combination with Phe-free L-amino acid supplements, and also pharmacological treatments, such as sapropterin dihydrochloride, which helps restoring Phe metabolism.

Diets for PKU patients require severely restricting or even eliminating foods of high phenylalanine content, such as meat, fish, nuts, cheese, legumes, and other dairy products.
Starchy foods such as potatoes, bread, pasta, and corn must be monitored. Infants may still be breastfed to provide all of the benefits of breast milk, but the quantity may need to be limited, resulting in necessary supplementation of missing nutrients. Many diet foods and diet soft drinks containing aspartame sweetener must also be avoided. Today most physicians recommend that PKU patients must keep monitoring their Phe levels throughout their entire life.

PKU and diet

Suitable food

The person can eat these foods without restriction.

 

Fruit, applesauce, lettuce, cucumbers, tomatoes, carrots, pumpkin, butter, margarine, low-protein bread, sugar, jelly-free gummy sweets, jam, fruit juice (e.g. apple and cranberry).

Suitable foods with restrictions

The person can only consume these foods in limited quantities

Various vegetables, potatoes, maize, bananas, bread, chips, rice, paprika.

Unsuitable food

The person must not take these foods.

 

 

Meat, sausages, poultry, pulses, nuts, soy products, dairy products, eggs.

Sapropterin Dipharma powder for oral solution

Thanks to the collaboration with Dr. Schircks, the pioneer of sapropterin synthesis, Sapropterin Dipharma is now available also in powder, with the great advantage of dissolving 25 times faster than normal tablets. In fact, it only takes 15 seconds!
Dipharma powder for oral solution is available in two different dosages: 100 or 500 mg of active ingredient. Dissolving in just a few seconds, it offers maximum flexibility in daily intake and compliance with the therapy prescribed by your doctor.

for dissolution sachet
0 seconds

How do I dissolve the powder solution?

The daily dose of sapropterin dihydrochloride is determined individually on the basis of the amount of phenylalanine in the blood. The drug is taken once a day during a meal, at the same time of day and preferably in the morning.

Senza titolo-1

Step 1

Pour the contents of the sachet(s) into a graduated glass by adding a defined amount of water.

bicchiere2

Step 2

Dissolve the powder while stirring for about 15 seconds.

bicchiere4

Step 3

And after only 15 seconds, the powder solution is ready to be taken.

About Us

Dipharma SA

Every day our top priority is taking care of people: patients, partners, employees. We provide high-quality drugs with improved properties such as an enhanced stability, to those who suffer from congenital metabolic disorders. We continuously listen to patients, parents, patient associations and physicians to learn about their needs and work on identifying sustainable solutions together. Thanks to our partners, we are able to reach patients all over the world, meeting unmet medical needs while keeping affordable prices.

FAQ

Questions and Answers

If the patient forgets to take it, he should not take a double dose. Consult your doctor or pharmacist.
If the patient has taken the wrong dose of Sapropterin Dipharma, side effects may occur. Please contact your doctor or pharmacist.
The patient should never stop the therapy without consulting their doctor, otherwise their health can deteriorate rapidly.

The diet agreed with your doctor should be followed. Always discuss changes to the diet.

The medicines may increase or decrease each other’s effect. You should therefore discuss the use of other medicines with your doctor or pharmacist.

Would you like more information?

Dipharma SA – Piazza Col. C. Bernasconi 5
6830 Chiasso, Switzerland

Phone +41 91 60 11 700 – Fax +41 91 60 11 701

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